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Limitations of Current Evidence for BRAF V600E-Mutant Metastatic NSCLC and Cross-Trial Comparisons

This segment analyzes key limitations of current evidence—including the non-randomized design of PHAROS and challenges of cross-trial comparison—while underscoring the ongoing need for better strategies in non-V600E mutations.

CNS Disease Considerations and Implications for Treatment Selection for BRAF V600E-Mutant Metastatic NSCLC

This segment examines treatment considerations for patients with CNS involvement, stressing individualized decisions due to limited dedicated CNS data for encorafenib/binimetinib in lung cancer.

The Future of Hemophilia Care

A forward-looking analysis of how nonfactor therapies are transforming patient quality of life, clinician-patient collaboration, and the broader healthcare ecosystem for hemophilia management.

Sanofi’s Qfitlia seems favorable for hemophilia with easier dosing and broad coverage | ASH 2025

Sanofi introduces Qfitlia earlier this year, a groundbreaking hemophilia treatment, offering flexible dosing and support for patients transitioning from existing therapies.

Sanofi highlights new BTK inhibitor data and strong results for ALTUVIIIO | ASH 2025

Jeff Schaffnit discusses Sanofi's advancements in BTK inhibitors and promising results for hemophilia A therapies at ASH 2025, enhancing treatment options.

Cytokine release syndrome and outpatient care of patients treated with CAR-T | ASH 2025

Clinicians are moving toward managing mild (Grade 1) cytokine release syndrome on an outpatient basis.

CAR T-cell treatment numbers may double by 2030 if committee is successful | ASH 2025

The CAR T Vision Steering Committee members wish to double the number of eligible patients receiving chimeric antigen receptor (CAR) T-cell therapy by 2030 through disease awareness and sustainable financing options, according to George Eastwood, Executive Director of the Emily Whitehead Foundation and recent CAR T Vision Steering Committee member.

The trend toward post-infusion outpatient care of patients treated with CAR-T | ASH 2025

As the number of patients with multiple myeloma and lymphoma treated with CAR-T therapy increases, health systems are shifting post-infusion care from inpatient to outpatient settings. Research presented at the annual meeting of the American Society of Hematology shows the change slices costs by $19,180.

The buzz about and the barriers to CAR T-cell therapy | ASH 2025

Chimeric antigen receptor (CAR) T-cell therapy can cure certain types of blood cancer, but cost and a general lack of awareness around the therapy are barriers to care, according to George Eastwood, Executive Director of the Emily Whitehead Foundation.

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